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. 2022 May 2;14:29. doi: 10.1186/s11689-022-09441-1

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Comparison of pan-cell type signaling networks in PFC. a Pan-cell type relative information flow showing signaling pathways identified in ASD PFC and controls. The pathways with greater information flow in ASD or controls were in cyan or red, respectively, with black indicating no significant differences. b and c Dot plots showing the difference in relative contribution of each cell type to outgoing (b) or incoming (c) signaling in ASD vs controls. Signaling on the left (a) with no difference was not included in (b) or (c)