Table 1.

Outline of different scenarios to incorporate uncertainty in the expected mortality

Scenario	cancer cohort used	size of general population used for population mortality	population mortality stratified by	corresponding conventional setting
A	full	original	age, year, sex	1
B	full	reduced to 10%	age, year, sex	1
C	full	reduced to 0.5%	age, year, sex	1
D	full	reduced to 0.05%	age, year, sex	1
E	reduced to 10%	reduced to 10%	age, year, sex	1Sa
F	full	original	age, year, sex, region	2
G	full	reduced to 10%	age, year, sex, region	2
H	full	reduced to 0.5%	age, year, sex, region	2
I	full	reduced to 0.05%	age, year, sex, region	2
J	reduced to 10%	reduced to 10%	age, year, sex, region	2Sa

^aS stands for small and refers to the setting to investigate what would be observed for a smaller population