Table 5.
Marginal estimates of 5-year RS and LLE for all investigated settings and scenarios. Marginal point estimates (PE) of 5-year relative survival (RS) and loss in life expectancy (LLE), with lower (LCI) and upper (UCI) confidence intervals, standard errors (SE) and relative % precision (RP) from different methods, settings and scenarios for including uncertainty in the general population mortality when estimating SEs. For settings 1 and 1S general population mortality rates are stratified by age, sex and calendar year. For settings 2 and 2S general population mortality rates are stratified by age, sex, calendar year and region. RP illustrates comparison of the conventional method to a bootstrap-based method
| Method | Setting / scenariob | 5-year Relative Survival (RS) | Loss in life expectancy (LLE)a | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| PE | SE | LCI | UCI | RPc | PE | SE | LCI | UCI | RP | ||
| Conventionald | 1 | 0.632 | 0.011 | 0.611 | 0.654 | 0.00 | 5.40 | 0.16 | 5.09 | 5.71 | 0.00 |
| Bootstrap-basede | A | 0.632 | 0.011 | 0.611 | 0.654 | 0.01 | 5.40 | 0.16 | 5.09 | 5.71 | 0.11 |
| B | 0.632 | 0.011 | 0.611 | 0.654 | 0.16 | 5.40 | 0.16 | 5.08 | 5.71 | 1.08 | |
| C | 0.632 | 0.011 | 0.610 | 0.655 | 3.08 | 5.40 | 0.17 | 5.06 | 5.74 | 21.82 | |
| D | 0.632 | 0.013 | 0.608 | 0.658 | 30.55 | 5.40 | 0.28 | 4.85 | 5.95 | 214.25 | |
| Conventional | 2 | 0.631 | 0.011 | 0.610 | 0.653 | 0.00 | 5.40 | 0.16 | 5.09 | 5.71 | 0.00 |
| Bootstrap-based | F | 0.631 | 0.011 | 0.610 | 0.653 | 0.02 | 5.40 | 0.16 | 5.09 | 5.71 | 0.11 |
| G | 0.631 | 0.011 | 0.610 | 0.653 | 0.15 | 5.40 | 0.16 | 5.09 | 5.72 | 1.09 | |
| H | 0.631 | 0.011 | 0.609 | 0.654 | 3.07 | 5.41 | 0.18 | 5.07 | 5.76 | 22.41 | |
| I | 0.631 | 0.013 | 0.606 | 0.656 | 30.06 | 5.58 | 0.32 | 4.95 | 6.21 | 313.01 | |
| Conventional | 1Sf | 0.619 | 0.037 | 0.550 | 0.695 | 0.00 | 5.19 | 0.51 | 4.19 | 6.19 | 0.00 |
| Bootstrap-based | E | 0.619 | 0.037 | 0.550 | 0.695 | 0.02 | 5.19 | 0.51 | 4.19 | 6.19 | 0.11 |
| Conventional | 2Sf | 0.617 | 0.037 | 0.549 | 0.693 | 0.00 | 5.19 | 0.51 | 4.19 | 6.19 | 0.00 |
| Bootstrap-based | J | 0.616 | 0.037 | 0.549 | 0.693 | -0.01 | 5.19 | 0.51 | 4.19 | 6.19 | 0.15 |
aLLE is presented in years
bSee Table 1 for information on the different settings and scenarios
cRP is presented in %
dConventional refers to the standard method for estimating SEs, where the general population mortality is assumed to be measured without uncertainty
eBootstrap-based refers to the parametric bootstrap approach used for including uncertainty in population mortality rates in the estimation of SEs
fS stands for small and refers to the setting to investigate what would be observed for a smaller population