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. 2019 Jan 11;9(3):1278–1283. doi: 10.1039/c8ra09203f

Synthesis of 4H-pyrimido[2,1-b]benzothiazole derivatives (IVa–m) in the presence of Fe3O4@ nano-cellulose/Cu(ii) under solvent-free condition at 80 °Ca appear here with headings as appropriate.

graphic file with name c8ra09203f-u2.jpg
Ent. R Prod. Time (min) Yieldb (%) M. P. Ref.
Found Report
1 H– IVa 45 84 178–180 177–179 17
2 4-NO2 IVb 30 97 171–173 170–172 22
3 4-Cl– IVc 30 95 87–89 86–88 21
4 4-Br– IVd 30 97 110–114 110–114 16
5 4-OH– IVe 60 82 210–212 210–212 22
6 2-NO2 IVf 45 88 122–125 122–125 23
7 2-Cl– IVg 40 87 124–126 125–127 17
8 2-EtO– IVh 60 75 171–175 171–175 23
9 3-NO2 IVi 35 93 222–224 222–224 21
10 3-OH– IVj 65 79 260–263 260–263 23
11 2,4-(Cl)2 IVk 45 85 133–135 133–135 17
12 2,4-(MeO)2 IVl 75 74 164–166 164–166 23
13 3,4-(OH)2 IVm 70 71 225–227 225–227 23
a

I (mmol) : II (mmol) : III (mmol) : Fe3O4@ nano-cellulose/Cu(ii) (g) is equal to 1 : 1 : 1 : 0.03.

b

Isolated yield.