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. 2019 Jan 9;9(3):1247–1259. doi: 10.1039/c8ra09036j

Fig. 5. Soybean protein-derived peptides supplementation promotes burn injury wound healing. (A) Injury area and wounds resulting from 30% TBSA burn injury were photographically captured in rats administered either PBS or soybean protein-derived peptides (burn + PBS and burn + peptides, respectively) immediately before burn trauma induction (week 0), 2, 4, 6 and 8 weeks post-burn injury. Quantitative scalar measurements of the burn wound area were measured (cm2) using Image-Pro Plus 5.1 software. (B) Relative burn wound extent (% wound area of total burn injured-area) was calculated as the absolute wound area (cm2) at either 4, 6 or 8 weeks post-injury/total approximated initial burn-injured area (cm2) × 100; (C) relative burn wound healing (% healed wound area of total wound) was calculated as (initial 4 week wound area (cm2) − wound area at a either 6 or 8 weeks post-injury (cm2)/initial wound area (cm2)) × 100; (D) exponential wound healing model wound closure predictions were projected. (E & F) CD-31, the marker of angiogenesis, was used to reveal the angiogenesis of burn wound (E) and quantitative analysis was done (F) at indicated groups. The star symbol (*) indicates a significant difference between burn injured rats administered PBS versus soybean protein-derived peptide (Student's t-test; p < 0.05).

Fig. 5