. Author manuscript; available in PMC: 2022 May 2.

Published in final edited form as: J Allergy Clin Immunol Pract. 2021 Oct 14;10(3):785–792.e5. doi: 10.1016/j.jaip.2021.09.047

Table 4.

ALSPAC: Odds of subsequent asthma ages 11–17 years, comparing high fasting insulin with low fasting insulin at age 8. All models adjusted for sex; models 2 and 3 adjusted for z-score BMI¹ at age 8. Models 1 and 2 include all participants, model 3 is limited to those with no asthma at age 8.

Models		Odds Ratio	95% CI	p	n	Observations
1	*All participants*
	High Fasting Insulin	1.59	1.12, 2.27	0.009	814	2236
	Female	1.11	0.80, 1.54	0.521

2	*All participants with BMI*
	High Fasting Insulin	1.51	1.05, 2.17	0.026	811	2236
	Female	1.11	0.80, 1.53	0.538
	zBMI	1.10	0.94, 1.29	0.243

3	*Limited to those with no asthma at age 8*
	High Fasting Insulin	2.14	1.10, 4.17	0.026	584²	1729
	Female	1.55	0.82, 2.95	0.180
	zBMI	0.99	0.72, 1.36	0.942

BMI included as z-scores from UK reference tables

584=811 minus 106 (with diagnosis of asthma at age 8) minus 121 (missing asthma information at age 8)