FIG. 2.

Reduction in keratitis SLE scores due to oral FCV or topical TFT. Groups of 10 rabbits each were inoculated with 2 × 10⁵ PFU of HSV-1 strain 17syn+ and treated with oral FCV at 250 mg/kg given b.i.d. by oral gavage or with topical drops of TFT given five times a day. The treatments were started at either 72 h (A) or 24 h (B) and continued for eight consecutive days. The keratitis was monitored by slit lamp microscopy, as indicated on the x axis of each graph. The placebo was water given orally, while BSS was given as topical drops. TFT SLE scores that are significantly different from FCV SLE scores (★; P = 0.0001), TFT and FCV SLE scores that exhibit no difference (▾), and TFT, FCV, and BSS SLE scores that exhibit no difference (▴) are noted on the x axis. The error bars represent the standard errors of the least-square means.