FIG. 4.

Quantitation of the HSV-1 genome copy number in the TG of latently infected rabbits previously treated with antiviral therapy or placebo. The TG were analyzed using real-time quantitative PCR with primer pairs and a probe for glycoprotein C using 100 ng of total TG DNA collected. (A) Average HSV-1 genome copy numbers in the TG of latently infected rabbits previously treated with no drug or 60, 120, or 250 mg of oral FCV per kg; (B) average HSV-1 genome copy numbers in the TG of latently infected rabbits previously treated with no drug, oral FCV, or topical TFT started at 24 or 72 h p.i. The error bars represent the standard errors of the least-square means, and the ★ indicates a P value of 0.0001.