TABLE 2.

Spontaneous and induced reactivation frequencies in latently infected rabbits after oral FCV treatment during acute infection

FCV treatment (mg/kg)c	Spontaneous reactivationa			Induced reactivationb
	Total no. of rabbitsd	% of positive swabs/rabbit (mean ± SE)e	Total no. of swabsf	Total no. of rabbits	% of positive swabs/rabbit (mean ± SE)	Total no. of swabs
0 (water)	6	26 ± 7	239	5	47 ± 10	70
60	4	30 ± 9	159	3	36 ± 20	42
120	5g	24 ± 9	182	4h	16 ± 8	49
250	5	24 ± 9	200	5	23 ± 9	70
500	4	28 ± 8	159	4	36 ± 7	56

^aSpontaneous reactivation indicates that virus was shed without an induction stimulus. 

^bIn induced reactivation, rabbits underwent transcorneal iontophoresis with 0.015% epinephrine. 

^cTreatment the rabbits received during acute infection; see Materials and Methods. 

^dNumber of rabbits included in each group. 

^eThe means and standard errors of the means are calculated from results for multiple rabbits in each group from one experiment. The spontaneous and induced reactivation experiments were conducted on the same set of rabbits. 

^fTotal number of swabs collected over the duration of the study; see Materials and Methods. 

^gOne rabbit died during the spontaneous swabbing experiment. 

^hOne rabbit had only one eye iontophoresed due to corneal scarring.