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. 2020 Nov 4;1(1):e7. doi: 10.1002/ski2.7
Cutaneous sequelae of obesity
Xerosis Increased water permeability of the skin leads to drier skin. 11
Hyperhidrosis Larger amounts of subcutaneous tissue impair temperature regulation. 12
Cutaneous microbiome Overweight individuals exhibit a less diverse microbiome with a relative increase in Corynebacterium. 19
Striae distensae Appear due to increased mechanical stress from adipose tissue and elevated serum adrenocorticosteroids. 22
Plantar hyperkeratosis Results from friction and increased pressure related to excess body weight. 10 , 23
Acanthosis nigricans A reliable indicator of hyperinsulinemia in obese individuals. 24
Acrochordons May signify underlying insulin resistance in obese patients. 26
Intertrigo Often overweight patients have several dermatoses superimposed upon one another. 28
Hidradenitis suppurativa The point prevalence of HS in obese is almost 20% as compared to 1% of the background population. 30
Psoriasis Excess body weight worsens existing psoriasis and impedes the efficacy of directed therapy, supporting the role of weight reduction in treating psoriasis. 31 , 32
Chronic venous insufficiency Severe chronic venous insufficiency is more likely to develop in obese individuals. 36
Secondary lymphodema Morbid obesity in particular is a risk factor for secondary lymphodema. 37
Pressure sores Immobile morbidly obese patients are more likely to experience pressure sores than their normal weight counterparts. 39
Cellulite Consequence of the normal, sex‐typical structural characteristics of the subdermal connective tissue in women compared to men. 40
Bariatric surgery Low levels of iron, zinc, copper, and vitamins A, E, folate and B12, may be observed with characteristic cutaneous sequalae. 45