TABLE 4.

Subgroup analyses

Items		TNF‐α	IL‐1β	IL‐6	IL‐17
Patients with adjuvant chemotherapy (n = 159)
HADS‐A score	r coefficient	0.325	0.297	0.157	0.071
	P value	<0.001	<0.001	0.048	0.375
HADS‐D score	r coefficient	0.360	0.352	0.152	0.179
	P value	<0.001	<0.001	0.055	0.024
Patients without adjuvant chemotherapy (n = 58)
HADS‐A score	r coefficient	0.269	0.238	0.116	0.212
	P value	0.041	0.073	0.385	0.111
HADS‐D score	r coefficient	0.239	0.181	0.153	0.151
	P value	0.070	0.174	0.250	0.257
Patients with TNM stage I (n = 62)
HADS‐A score	r coefficient	0.241	0.199	0.017	0.188
	P value	0.059	0.121	0.896	0.144
HADS‐D score	r coefficient	0.272	0.247	0.105	0.173
	P value	0.032	0.053	0.416	0.179
Patients with TNM stage II (n = 84)
HADS‐A score	r coefficient	0.197	0.331	0.172	0.099
	P value	0.073	0.002	0.117	0.368
HADS‐D score	r coefficient	0.286	0.307	0.233	0.158
	P value	0.008	0.004	0.033	0.151
Patients with TNM stage III (n = 71)
HADS‐A score	r coefficient	0.431	0.280	0.235	0.064
	P value	<0.001	0.018	0.048	0.595
HADS‐D score	r coefficient	0.397	0.362	0.106	0.214
	P value	0.001	0.002	0.378	0.074

Abbreviations: HADS‐A, Hospital Anxiety and Depression Scale‐anxiety; HADS‐D, Hospital Anxiety and Depression Scale‐depression; IL, interleukin; TNF, tumor necrosis factor.