TABLE 3.
Variables | Univariate logistic regression | Multivariate logistic regression | |||||
---|---|---|---|---|---|---|---|
OR (95%CI) | p‐value | OR (95%CI) | p‐value | ||||
Sex | Male | 0.37 | 0.25–0.54 | <0.001 | 0.32 | 0.20–0.53 | <0.001 |
Female | REF | REF | |||||
Age | ≥65 years | 0.48 | 0.33–0.70 | <0.001 | 0.50 | 0.33–0.76 | <0.001 |
<65 years | REF | REF | |||||
Smoking status | Ex/current smoker | 0.64 | 0.45–0.93 | 0.018 | 1.25 | 0.77–2.02 | 0.360 |
Non‐smoker | REF | ||||||
Disease | CFIP without AE | 0.40 | 0.24–0.64 | <0.001 | 0.71 | 0.41–1.26 | 0.246 |
AE of CFIP/ARDS | 0.34 | 0.11–1.09 | 0.070 | 0.65 | 0.18–2.32 | 0.510 | |
Others | 0.38 | 0.23–0.63 | <0.001 | 0.68 | 0.39–1.20 | 0.184 | |
Sarcoidosis | REF | REF | |||||
Bronchus laterality | Left | 0.47 | 0.32–0.69 | <0.001 | 0.46 | 0.30–0.71 | <0.001 |
Right | REF | REF | |||||
Bronchus location | Others | 0.47 | 0.31–0.71 | <0.001 | 0.41 | 0.25–0.65 | <0.001 |
Middle/lingula | REF | REF | |||||
%VC | <65% | 0.62 | 0.42–0.93 | 0.021 | 0.63 | 0.40–1.00 | 0.050 |
≥65% | REF | REF | |||||
FEV1/FVC | <80% | 0.59 | 0.41–0.84 | 0.003 | 0.42 | 0.28–0.63 | <0.001 |
≥80% | REF | REF |
Note: The C‐statistic showed good discrimination in the multivariate logistic model (C = 0.73, 95% CI: 0.69–0.78).
Abbreviations: AE, acute exacerbation; ARDS, acute respiratory distress syndrome; BALF, bronchoalveolar lavage fluid; CFIP, chronic fibrotic interstitial pneumonia; CI, confidence interval; FEV1/FVC, forced expiratory volume in 1 s divided by forced vital capacity; VC, vital capacity.