Table 1. Cytokine panel and CRP between ICU, non-ICU patients and healthy volunteers.
Analyte | ICU patients | Non-ICU patients | Healthy Volunteers | P value |
---|---|---|---|---|
(n = 46) | (n = 30) | (n = 24) | ||
IL-1β (ng/L) | 0.35 (0.32–0.66) | 0.32 (0.32–0.32) | 0.11 (0.05–0.21) | <0.0001 |
IL-6 (ng/L) | 36.50 (16.07–127.50) | 17.45 (7.90–51.60) | 0.99 (0.62–1.42) | <0.0001 |
IL-8 (ng/L) | 72.20 (49.47–115.50) | 40.60 (29.00–60.50) | 10.55 (7.58–15.67) | <0.0001 |
TNFα (ng/L) | 25.00 (18.08–35.75) | 16.35 (14.10–19.80) | 9.83 (8.40–11.27) | <0.0001 |
CRP (mg/L) | 92.5 (54.9–137.3) | 105.0 (68.2–146.2) | 1.00 (1.00–1.7) | <0.0001 |
Data is presented as median (IQR).
Abbreviations: IL-1β, interleukin-1β; IL-6, interleukin-6; IL-8, interleukin-8; TNFα, tumour necrosis factor alpha; CRP, C-reactive protein.