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. 2022 May 2;17(5):e0266652. doi: 10.1371/journal.pone.0266652

Table 1. Cytokine panel and CRP between ICU, non-ICU patients and healthy volunteers.

Analyte ICU patients Non-ICU patients Healthy Volunteers P value
(n = 46) (n = 30) (n = 24)
IL-1β (ng/L) 0.35 (0.32–0.66) 0.32 (0.32–0.32) 0.11 (0.05–0.21) <0.0001
IL-6 (ng/L) 36.50 (16.07–127.50) 17.45 (7.90–51.60) 0.99 (0.62–1.42) <0.0001
IL-8 (ng/L) 72.20 (49.47–115.50) 40.60 (29.00–60.50) 10.55 (7.58–15.67) <0.0001
TNFα (ng/L) 25.00 (18.08–35.75) 16.35 (14.10–19.80) 9.83 (8.40–11.27) <0.0001
CRP (mg/L) 92.5 (54.9–137.3) 105.0 (68.2–146.2) 1.00 (1.00–1.7) <0.0001

Data is presented as median (IQR).

Abbreviations: IL-1β, interleukin-1β; IL-6, interleukin-6; IL-8, interleukin-8; TNFα, tumour necrosis factor alpha; CRP, C-reactive protein.