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. 2022 May 2;17(5):e0266652. doi: 10.1371/journal.pone.0266652

Table 3. Cytokines, PCT and CRP in ICU vs. non-ICU patients with COVID-19.

Analyte ICU patients Non-ICU patients P value
(n = 46) (n = 30)
IL-1β (ng/L) 0.35 (0.32–0.66) 0.32 (0.32–0.32) 0.07
IL-6 (ng/L) 36.50 (16.07–127.50) 17.45 (7.90–51.60) 0.03
IL-8 (ng/L) 72.20 (49.47–115.50) 40.60 (29.00–60.50) <0.001
TNFα (ng/L) 25.00 (18.08–35.75) 16.35 (14.10–19.80) <0.0001
PCT (μg/L) 0.65 (0.30–1.98)
  • 0.18 (0.12–0.29)

<0.0001
CRP (mg/L) 92.5 (54.9–137.3) 105.0 (68.2–146.2) 0.77

Data is presented as median (IQR).

Abbreviations: PCT, procalcitonin; IL-1β, interleukin-1β; IL-6, interleukin-6; IL-8, interleukin-8; TNFα, tumour necrosis factor alpha; CRP, C-reactive protein.