Table 4. Human genomic variants with overlapping associations to TTI2 expression and phenotypes.

Variant ID	eQTL beta direction	eQTL data sets	Associated trait	Trait ID	GWAS p value	GWAS beta direction	Risk Frequency*
rs10094645	increase	Artery_Aorta, Muscle_Skeletal, Testis, Thyroid, Whole_Blood	blood protein measurement	EFO_0007937	4E-23	decrease	0.594
rs2732317	increase	Artery_Aorta, Testis, Thyroid, Whole_Blood	blood protein measurement	EFO_0007937	3E-77	decrease	0.612
rs2732260	increase	Monocyte	frontotemporal dementia, memory impairment	Orphanet_282 EFO_0001072	1E-6	NA	0.03
rs2732259	increase	Esophagus_Muscularis, Muscle_Skeletal, Testis, Whole_Blood	hypoxanthine measurement	EFO_0010500	7E-6	increase	0.619*
rs6996562	increase	Artery_Aorta, Testis, Whole_Blood	pulse pressure measurement	EFO_0005763	2E-10	increase	0.473
rs7845722	increase	Artery_Aorta, Muscle_Skeletal, Testis, Whole_Blood	pulse pressure measurement	EFO_0005763	1E-9	increase	0.4
rs1568119	decrease	Monocyte	stem cell factor measurement	EFO_0008291	1E-7	increase	0.08*