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. Author manuscript; available in PMC: 2023 Apr 29.
Published in final edited form as: Circ Res. 2022 Apr 28;130(9):1382–1403. doi: 10.1161/CIRCRESAHA.122.319967

Figure 2. Left Atrial Dysfunction Correlates with Pulmonary Vascular Resistance and Compliance in Heart Failure.

Figure 2.

Left panel: In patients with HFpEF, worse LA reservoir strain (indicative of the inability of the LA to fill from the pulmonary veins during ventricular systole) is associated with increased PVR. Middle panel: In patients with HFpEF and HFrEF, lower LA emptying fraction (indicative of worse LA function) is also associated with elevated PVR. Right panel: Lower LA emptying fraction is also associated with reduced PA compliance in both HFpEF and HFrEF. Reproduced with permission from Freed, et al. Circulation: Cardiovascular Imaging 2016 and Melenovsky, et al. Circulation: Heart Failure 2015.