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. 2019 Feb 12;9(9):5158–5163. doi: 10.1039/c9ra00653b

Effect of temperature on the synthesis of 2,4,6-triphenylpyridinea.

Entry Temp. (°C) Yieldb (%)
1 Room temp.
2 45 36
3 60 67
4 80 93
5 85 93
a

Reaction condition: benzaldehyde (1 mmol), acetophenone (2 mmol), ammonium acetate (1.5 mmol), HNTf2 (1 mol%) at different temperature for 50 min under solvent-free conditions.

b

Isolated yield.