Fig. 4. PCoA and RDA analyses. (A) The different colors in the PCoA analysis represent different groups, and the closer the sample distance is, the more similar the microbial composition between the samples is, and the smaller the difference is. (S, small intestine; C, colon; F, feces); (B) RDA analysis between bacterial species and related factors (amylase, lipase, TNF-α, IL-1β and IL-6, and the histological scores) in fecal samples of AP and SO rats.