Effect of iron supplementation on antioxidant activity in liver of rats in different groupsa.
Group | Dosage (mg Fe per kg bw) | SOD (U per mg prot) | CAT (U per mg prot) | GSH-PX (activity units) | T-AOC (U per mg prot) | MDA (nmol mg−1 prot) |
---|---|---|---|---|---|---|
Normal control | 0 | 246.69 ± 12.31a | 70.58 ± 4.55a | 440.56 ± 22.87a | 1.83 ± 0.09a | 0.79 ± 0.06c |
Anemia model | 0 | 123.72 ± 13.19c | 45.83 ± 2.30c | 299.06 ± 10.83c | 0.97 ± 0.06c | 1.12 ± 0.07a |
Ferrous gluconate | 4 | 236.03 ± 19.75ab | 66.75 ± 2.86ab | 417.45 ± 14.55ab | 1.80 ± 0.08ab | 0.83 ± 0.08bc |
FeSO4 | 4 | 219.36 ± 16.23b | 63.62 ± 3.50b | 411.41 ± 31.81b | 1.72 ± 0.10b | 0.91 ± 0.05b |
LD-AOS–iron | 1 | 207.67 ± 17.02b | 60.11 ± 4.74b | 396.58 ± 12.64b | 1.63 ± 0.05b | 0.93 ± 0.07b |
MD-AOS–iron | 2 | 238.79 ± 23.04ab | 67.51 ± 2.33ab | 419.02 ± 14.13ab | 1.76 ± 0.08ab | 0.84 ± 0.06bc |
HD-AOS–iron | 4 | 251.02 ± 17.56a | 72.82 ± 5.95a | 437.01 ± 23.84a | 1.85 ± 0.09a | 0.79 ± 0.04c |
The results are presented as the mean ± SD (n = 12). Different lower-case roman letters in the same column indicate a significant difference between different groups (p < 0.05).