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. 2019 Feb 11;9(9):5053–5063. doi: 10.1039/c8ra08451c

Effect of iron supplementation on antioxidant activity in liver of rats in different groupsa.

Group Dosage (mg Fe per kg bw) SOD (U per mg prot) CAT (U per mg prot) GSH-PX (activity units) T-AOC (U per mg prot) MDA (nmol mg−1 prot)
Normal control 0 246.69 ± 12.31a 70.58 ± 4.55a 440.56 ± 22.87a 1.83 ± 0.09a 0.79 ± 0.06c
Anemia model 0 123.72 ± 13.19c 45.83 ± 2.30c 299.06 ± 10.83c 0.97 ± 0.06c 1.12 ± 0.07a
Ferrous gluconate 4 236.03 ± 19.75ab 66.75 ± 2.86ab 417.45 ± 14.55ab 1.80 ± 0.08ab 0.83 ± 0.08bc
FeSO4 4 219.36 ± 16.23b 63.62 ± 3.50b 411.41 ± 31.81b 1.72 ± 0.10b 0.91 ± 0.05b
LD-AOS–iron 1 207.67 ± 17.02b 60.11 ± 4.74b 396.58 ± 12.64b 1.63 ± 0.05b 0.93 ± 0.07b
MD-AOS–iron 2 238.79 ± 23.04ab 67.51 ± 2.33ab 419.02 ± 14.13ab 1.76 ± 0.08ab 0.84 ± 0.06bc
HD-AOS–iron 4 251.02 ± 17.56a 72.82 ± 5.95a 437.01 ± 23.84a 1.85 ± 0.09a 0.79 ± 0.04c
a

The results are presented as the mean ± SD (n = 12). Different lower-case roman letters in the same column indicate a significant difference between different groups (p < 0.05).