IBS solid forms obtained by solvent at two different temperatures and properties of the solvents used.
| Solvent | Solid form 72 h, 25 °C | Solid form 72 h, 40 °C | Relative permittivity εa | Dipole moment μa | Electrostatic factor EFb |
|---|---|---|---|---|---|
| Chloroform | Form A | Form A | 4.81 | 1.15 | 5.53 |
| Ethyl acetate | Form A | Form A | 6.02 | 1.88 | 11.32 |
| Isopropyl alcohol | Form A | Form A | 17.9 | 1.66 | 29.71 |
| Acetone | Form A | Form A | 20.7 | 2.85 | 58.99 |
| Ethanol | Form A | Form A | 24.5 | 1.69 | 41.40 |
| Methanol | Form A | Form A | 32.7 | 1.70 | 55.59 |
| Nitromethane | Form B | Form B | 35.9 | 3.54 | 127.09 |
| Acetonitrile | Form B | Form B | 37.5 | 3.45 | 129.38 |
| DMF | Form B | Form B | 36.7 | 3.86 | 141.66 |
| Water | Form B | Form B | 80.1 | 1.82 | 145.78 |
| DMSO | Form B | Form B | 46.7 | 3.90 | 182.13 |
a
The reported relative permittivity (ε) and the dipole moment (μ) values were obtained from literature.32
b
The electrostatic factor is calculated as the product of μ and ε.