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. 2019 Feb 8;9(9):4917–4924. doi: 10.1039/c8ra10074h

Structures and their relative activity of DC_HG24-01 and its analoguesa.

graphic file with name c8ra10074h-u1.jpg
Entry Compound R1 R2 IC50 (μM)
1 DC_HG24 graphic file with name c8ra10074h-u2.jpg graphic file with name c8ra10074h-u3.jpg 12.7 ± 0.9
2 DC_HG24-01 graphic file with name c8ra10074h-u4.jpg graphic file with name c8ra10074h-u5.jpg 3.1 ± 0.2
3 DC_HG24-02 graphic file with name c8ra10074h-u6.jpg graphic file with name c8ra10074h-u7.jpg 9.1 ± 1.0
4 DC_HG24-03 graphic file with name c8ra10074h-u8.jpg graphic file with name c8ra10074h-u9.jpg 31.3 ± 0.8
5 DC_HG24-04 graphic file with name c8ra10074h-u10.jpg graphic file with name c8ra10074h-u11.jpg 14.2 ± 2.1
6 DC_HG24-05 graphic file with name c8ra10074h-u12.jpg graphic file with name c8ra10074h-u13.jpg >100
7 DC_HG24-06 graphic file with name c8ra10074h-u14.jpg graphic file with name c8ra10074h-u15.jpg >100
a

Data in table is presented as mean ± SD, n = 3.