TABLE 2.
Pearson activity correlations at EC50 and EC90 levels between DBB and other antimalarialsa
| Drug correlated with DBB | n | Correlation at EC50
|
Correlation at EC90
|
||
|---|---|---|---|---|---|
| r | P | r | P | ||
| Benflumetol | 154 | 0.687 | <0.001 | 0.463 | <0.001 |
| Mefloquine | 33 | 0.950 | <0.001 | 0.823 | <0.001 |
| Chloroquine | 32 | 0.064 | >0.05 | −0.018 | >0.05 |
| Artemisinin | 33 | 0.474 | <0.01 | 0.261 | >0.05 |
| Quinine | 31 | 0.408 | <0.05 | 0.346 | >0.05 |
| Atovaquone | 25 | 0.641 | <0.001 | 0.381 | >0.05 |
Significant correlations suggest similarities in the mode of action and may reflect cross-sensitivities. P values in bold are significant.