Skip to main content
. 2019 Feb 12;9(10):5362–5376. doi: 10.1039/c8ra09652j

Selected combinations of two drugs that inhibit the cell proliferation by 50% (CC50, μM) towards wild type and cisplatin-resistant CCRF-CEM and A2780 cells.

CC50, μM
Compound CCRF-CEM-wt CCRF-CEM-res A2780-wt A2780-res
C0 + CDDP 0.26 + 0.40 0.50 + 5; 0.75 + 2 0.075 + 2.5 0.26 + 6.41
CDDP + GSH 0.32 + 200 10 + 300 7.0 + 400 5.3 + 50; 12 + 350; 21 + 900
C0 + GSH 0.42 + 200 0.35 + 300 0.10 + 300 0.26 + 200