Selected combinations of two drugs that inhibit the cell proliferation by 50% (CC50, μM) towards wild type and cisplatin-resistant CCRF-CEM and A2780 cells.
CC50, μM | ||||
---|---|---|---|---|
Compound | CCRF-CEM-wt | CCRF-CEM-res | A2780-wt | A2780-res |
C0 + CDDP | 0.26 + 0.40 | 0.50 + 5; 0.75 + 2 | 0.075 + 2.5 | 0.26 + 6.41 |
CDDP + GSH | 0.32 + 200 | 10 + 300 | 7.0 + 400 | 5.3 + 50; 12 + 350; 21 + 900 |
C0 + GSH | 0.42 + 200 | 0.35 + 300 | 0.10 + 300 | 0.26 + 200 |