. 2019 Feb 18;9(11):5948–5957. doi: 10.1039/c8ra10283j

Effects of graded levels of CHC on serum immunological parameters in weaned piglets^a (n = 6).

Items	MMT, mg kg⁻¹, 1000	CHC, mg kg⁻¹						SEM	P value
Items	MMT, mg kg⁻¹, 1000	0	500		1000	1500	2000	SEM	ANOVA	Linear	Quadratic
0 d ^b
IgM, g L⁻¹	0.70	0.76	0.94	0.84		0.71	0.88	0.07	0.25	0.14	0.37
IgA, g L⁻¹	1.08	1.06	0.94	0.91		1.04	0.83	0.13	0.75	0.54	0.89
IgG, g L⁻¹	9.84	8.34	9.53	10.13		9.18	9.06	0.36	0.09	0.28	0.30
IL-1β, pg mL⁻¹	51.77	55.50	57.93	54.30		54.51	54.94	1.17	0.13	0.49	0.09
IFN-γ, pg mL⁻¹	68.49	71.05	76.53	70.80		75.17	75.83	2.80	0.26	0.06	0.85

14 d
IgM, g L⁻¹	0.85^c	0.77^c	1.54^ab	1.76^a		1.13^bc	1.15^bc	0.16	<0.01	0.09	0.67
IgA, g L⁻¹	1.42	1.14	1.05	1.17		1.37	1.07	0.14	0.34	0.48	0.21
IgG, g L⁻¹	8.63	9.60	10.23	11.10		9.26	9.45	0.73	0.26	0.88	0.85
IL-1β, pg mL⁻¹	48.14	53.45	49.15	57.57		58.71	61.32	5.10	0.38	0.77	0.13
IFN-γ, pg mL⁻¹	58.61	66.17	63.42	60.12		59.24	61.97	2.90	0.45	0.71	0.12

28 d
IgM, g L⁻¹	0.78	1.04	1.39	1.44		0.94	1.06	0.19	0.15	0.66	0.56
IgA, g L⁻¹	1.29	1.27	1.12	1.19		1.46	1.05	0.12	0.23	0.18	0.34
IgG, g L⁻¹	10.54^a	8.66^b	10.85^a	10.70^a		9.67^ab	9.96^ab	0.48	0.03	0.02	0.58
IL-1β, pg mL⁻¹	75.60^ab	65.81^b	92.96^a	91.37^a		66.81^b	60.27^b	7.31	0.01	0.37	0.28
IFN-γ, pg mL⁻¹	62.28	62.62	62.54	61.05		59.56	59.69	2.34	0.87	0.82	0.19

^a,b,cMeans within the same row without common superscripts differ significantly (P < 0.05).

IgM immune globulin M, IgA immune globulin A, IgG immune globulin G, IL-1β interleukin-1β, IFN-γ interferon-γ.

Effects of graded levels of CHC on serum immunological parameters in weaned pigletsa (n = 6).