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. Author manuscript; available in PMC: 2022 Aug 3.
Published in final edited form as: Nat Neurosci. 2022 Feb 3;25(2):238–251. doi: 10.1038/s41593-021-01005-1

Figure 8. Pmp2-depleted fascicles identified in sciatic nerve of ALS patients.

Figure 8.

(a-c) Immunostaining of cross-sections of human sciatic nerves with no peripheral neuropathy reported. Only a sub-population of SCs expressed PMP2 across the three samples. (d-f) Immunostaining of cross-section of human ALS sciatic nerve. PMP2+ staining is vastly decreased in all three ALS samples. PMP2 (green), MBP (red), DAPI (blue). Scale bar = 100um.