Antiviral activities of the target compounds against TMV in vivo at 500 μg mL−1.
| Compd. | Curative activitya (%) | Protective activitya (%) | Inactivation activitya (%) |
|---|---|---|---|
| 4a | 49.4 ± 0.8 | 46.3 ± 7.9 | 60.9 ± 2.4 |
| 4b | 40.4 ± 0.8 | 58.7 ± 1.3 | 43.8 ± 4.2 |
| 4c | 30.6 ± 0.4 | 34.3 ± 4.0 | 23.3 ± 1.6 |
| 4d | 48.3 ± 1.3 | 44.6 ± 4.4 | 55.2 ± 1.8 |
| 4e | 56.4 ± 1.0 | 41.7 ± 4.6 | 46.3 ± 0.1 |
| 4f | 55.6 ± 2.3 | 38.7 ± 2.4 | 50.8 ± 1.9 |
| 4g | 54.9 ± 4.6 | 55.5 ± 4.9 | 64.6 ± 0.8 |
| 4h | 53.6 ± 2.6 | 46.9 ± 2.8 | 51.6 ± 1.7 |
| 4i | 54.9 ± 9.7 | 42.2 ± 0.5 | 52.1 ± 2.5 |
| 4j | 57.1 ± 1.1 | 51.7 ± 0.1 | 62.9 ± 0.3 |
| 4k | 55.3 ± 0.6 | 56.8 ± 0.9 | 86.8 ± 1.0 |
| 4l | 62.7 ± 0.3 | 58.6 ± 1.3 | 62.6 ± 2.0 |
| 4m | 45.2 ± 4.3 | 39.5 ± 3.2 | 51.1 ± 1.1 |
| 4n | 44.1 ± 1.2 | 51.1 ± 0.3 | 23.9 ± 9.2 |
| 4o | 61.4 ± 1.4 | 55.9 ± 0.3 | 23.3 ± 0.1 |
| 4p | 37.8 ± 1.7 | 44.4 ± 2.3 | 40.1 ± 1.7 |
| 4q | 44.8 ± 0.5 | 47.4 ± 4.8 | 43.2 ± 4.0 |
| 4r | 41.7 ± 1.8 | 20.1 ± 0.8 | 54.6 ± 2.9 |
| 4s | 43.1 ± 0.5 | 27.3 ± 1.0 | 51.2 ± 2.2 |
| 4t | 56.1 ± 0.4 | 51.3 ± 1.9 | 46.2 ± 7.6 |
| 4u | 65.6 ± 0.1 | 62.7 ± 0.7 | 51.6 ± 0.7 |
| 4v | 50.7 ± 1.8 | 56.2 ± 2.3 | 38.8 ± 2.6 |
| 4w | 60.6 ± 0.5 | 50.8 ± 0.1 | 49.6 ± 0.9 |
| Ningnanmycinb | 45.7 ± 2.6 | 53.4 ± 2.4 | 77.3 ± 1.6 |
a
Average of three replicates.
b
A commercial agricultural antiviral agent ningnanmycin was used for comparison of antiviral activities.