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. 2019 Feb 19;9(11):6011–6020. doi: 10.1039/c9ra00618d

EC 50 values of the 4g, 4k, 4l and 4u against TMV in vivoa.

Compd. Against TMV Regression equation r 2 EC50
4g Curative activity y = 0.3961x + 4.5075 0.9707 17.5 ± 0.34
Protection activity y = 0.4213x + 3.9441 0.9534 320.8 ± 0.19
Inactivation activity y = 0.5973x + 4.0952 0.9654 32.7 ± 0.03
4k Curative activity y = 0.3432x + 4.5403 0.9006 21.8 ± 0.05
Protection activity y = 0.2912x + 4.2541 0.9415 364.3 ± 0.21
Inactivation activity y = 0.2248x + 4.9103 0.9939 2.5 ± 0.04
4l Curative activity y = 0.3387x + 4.6487 0.9347 10.9 ± 0.02
Protection activity y = 0.3195x + 4.3930 0.9078 79.4 ± 0.22
Inactivation activity y = 0.5142x + 4.1551 0.9541 43.9 ± 0.03
4u Curative activity y = 0.4456x + 4.1718 0.9690 72.2 ± 4.04
Protection activity y = 0.4467x + 4.2318 0.9440 52.4 ± 0.06
Inactivation activity y = 0.2934x + 4.4604 0.9156 68.9 ± 0.19
Ningnanmycinb Curative activity y = 0.4415x + 4.1563 0.9720 81.4 ± 0.28
Protection activity y = 0.4732x + 4.0939 0.9097 82.2 ± 0.05
Inactivation activity y = 0.4591x + 4.9815 0.9056 1.1 ± 0.02
a

Average of three replicates.

b

A commercial agricultural antiviral agent ningnanmycin was used for comparison of antiviral activities.