EC 50 values of the 4g, 4k, 4l and 4u against TMV in vivoa.
Compd. | Against TMV | Regression equation | r 2 | EC50 |
---|---|---|---|---|
4g | Curative activity | y = 0.3961x + 4.5075 | 0.9707 | 17.5 ± 0.34 |
Protection activity | y = 0.4213x + 3.9441 | 0.9534 | 320.8 ± 0.19 | |
Inactivation activity | y = 0.5973x + 4.0952 | 0.9654 | 32.7 ± 0.03 | |
4k | Curative activity | y = 0.3432x + 4.5403 | 0.9006 | 21.8 ± 0.05 |
Protection activity | y = 0.2912x + 4.2541 | 0.9415 | 364.3 ± 0.21 | |
Inactivation activity | y = 0.2248x + 4.9103 | 0.9939 | 2.5 ± 0.04 | |
4l | Curative activity | y = 0.3387x + 4.6487 | 0.9347 | 10.9 ± 0.02 |
Protection activity | y = 0.3195x + 4.3930 | 0.9078 | 79.4 ± 0.22 | |
Inactivation activity | y = 0.5142x + 4.1551 | 0.9541 | 43.9 ± 0.03 | |
4u | Curative activity | y = 0.4456x + 4.1718 | 0.9690 | 72.2 ± 4.04 |
Protection activity | y = 0.4467x + 4.2318 | 0.9440 | 52.4 ± 0.06 | |
Inactivation activity | y = 0.2934x + 4.4604 | 0.9156 | 68.9 ± 0.19 | |
Ningnanmycinb | Curative activity | y = 0.4415x + 4.1563 | 0.9720 | 81.4 ± 0.28 |
Protection activity | y = 0.4732x + 4.0939 | 0.9097 | 82.2 ± 0.05 | |
Inactivation activity | y = 0.4591x + 4.9815 | 0.9056 | 1.1 ± 0.02 |
Average of three replicates.
A commercial agricultural antiviral agent ningnanmycin was used for comparison of antiviral activities.