Table 1.

Selected studies reporting the pharmacokinetics of oral bergapten (1.2 mg/kg).

Reference	Formulation	Pharmacokinetic parameter
		C max(ng/L)	t max (h)	AUC (ng/L·h)	t 1/2 (h)
Nonfasted conditions
Aubin et al. [16]	M	320	0.9	ND	ND
	UM	86	3.8	ND	ND
Stolk et al. [17]	M	322	2.7	942	ND
	UM	108	3.3	276	ND
Treffel et al. [18]	M	249	1.5	890	3.2
	UM	68	3.0	272	2.2
Fasted conditions
Brodie et al. [19]	M	177	1.6	433	1.4
	UM	19	3.4	64	2.0
[20]	M	32	2.0	140	1.7
	LS	71	2.0	262	2.3

AUC: area under the plasma concentration curve; C_max: maximum plasma concentration; LS: gelatin encapsulated liquid suspension; M: micronized; ND: not described; t_max: time to C_max; UM: unmicronized.