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The effect of HDS-1-derived flavonoids (HDS-2) and lignoids (HDS-3) on the efflux of paclitaxel (Papp) in the Caco-2 permeability experiment. ∗P < 0.05 versus Papp of AP–BL in PTX only. #P < 0.05 versus Papp of BL–AP in PTX only. The effect of HDS-2 and HDS-3 on regulating the efflux ratio (ER) of paclitaxel in the Caco-2 bidirectional transport experiment.
