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LIRA slows down the progression of AS in DM rats by inhibiting vascular calcification. (a) HE staining of the thoracic aorta showed the effect of LIRA on the progression of AS in DM rats (400x). (b) ALP activity detection in vitro. (c) Calcium content detection. Data were from three independent experiments expressed as mean ± standard deviation. ∗P < 0.01 vs. control; #P < 0.01 vs. DM + AS. In group DM + AS, 0 months vs. 2 months (P < 0.01) and 2 months vs. 4 months (P < 0.01).
