Synergy test. Antibacterial activity of peptides combined with antibiotics. C (ciprofloxacin), V (vancomycin)a.
| Bacterial strain | Antibiotic | Peptide | MICA | MICP | A | P | FIC, index | MICA/A | Activity | |
|---|---|---|---|---|---|---|---|---|---|---|
| Gram negative | E. coli 25 922 | C | LfcinB (20–25)2 | 0.09 | 25 | 0.006 | 0.75 | 0.09 | 15 | S |
| E. coli 11 775 | C | LfcinB (21–25)Pal | 0.04 | 50 | 0.020 | 50 | 1.50 | 2 | I | |
| P. aeruginosa 27 853 | C | LfcinB (20–25)4 | 0.40 | 100 | 0.020 | 3.1 | 0.09 | 20 | S | |
| Gram positive | E. faecalis 29 212 | V | LfcinB (20–30)4 | 6.4 | 400 | 0.200 | 12.5 | 0.06 | 32 | S |
| LfcinB (21–25)Pal | 6.4 | 200 | 0.100 | 25 | 0.14 | 64 | S | |||
| S. aureus 25 923 | V | LfcinB (21–25)Pal | 6.4 | 400 | 0.060 | 0.06 | 0.01 | 107 | S | |
| LfcinB (20–25)4 | 6.4 | 100 | 0.100 | 3.1 | 0.04 | 64 | S | |||
MICA, MICP,A and P in μg mL−1. S: synergy; I: indifference.