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. 2022 Apr 29;4(5):e0682. doi: 10.1097/CCE.0000000000000682

TABLE 3.

Sequential Organ Failure Assessment Description

Variable Events (n) Are Under the Curve (%) (95% CI) se Cutoffb Sensitivity % (95% CI) Specificity % (95% CI) p OR (95% CI) p
12 mo
 SOFA at 24 hra 1,379 81.6 (75.1–88.1) 3.3 4.5 62.3 (49.8–73.4) 74 (71.5–76.3) < 0.0001 1.203 (1.103–1.313) < 0.001
 SOFA at 48 hra 968 85.2 (79.8–90.6) 2.7 4.5 73.1 (59.8–83.2) 70.9 (67.8–73.7) < 0.0001 1.211 (1.105–1.327) < 0.001
 Mean SOFAa 1,379 82.7 (76.1–89.3) 3.4 4.55 55.7 (43.3–67.5) 84.5 (82.4–86.3) < 0.0001 1.266 (1.157–1.385) < 0.001
 Highest SOFAa 1,379 82.7 (76.2–89.2) 3.3 5.5 59 (46.5–70.5) 78.9 (76.7–81.1) < 0.0001 1.224 (1.131–1.325) < 0.001
24 mo
 SOFA at 24 hra 899 73.3 (67.5–79.2) 2.9 4.5 59.1 (48.7–68.8) 71.4 (67.7–74.9) < 0.0001 1.130 (1.001–1.276) 0.048
 SOFA at 48 hra 652 75.7 (69.4–82.1) 3.3 4.5 67.1 (55.9–76.6) 71.9 (67.6–75.9) < 0.0001 1.158 (1.024–1.310) 0.020
 Mean SOFAa 899 73.8 (67.7–79.9) 3.1 3.23 63.6 (53.2–72.9) 69.8 (66.1–73.3) < 0.0001 1.184 (1.038–1.350) 0.043
 Highest SOFAa 899 74.3 (68.4–80.2) 3 4.5 65.9 (55.5–74.9) 66.6 (62.7–70.2) < 0.0001 1.136 (1.016–1.270) 0.025

OR = odds ratio, SOFA = Sequential Organ Failure Assessment.

aAdjusted for age, gender, diagnosis, procedure, comorbidities (hypertension, dyslipidemia, diabetes mellitus, ischemic cardiopathy, peripheral artery disease, cerebrovascular disease, chronic kidney disease, pulmonary disease), left ventricular function, timing of surgery, and previous cardiac surgery.

bOptimal cutoff value for the best sensitivity and specificity.