TABLE 3.
Variable | Events (n) | Are Under the Curve (%) (95% CI) | se | Cutoffb | Sensitivity % (95% CI) | Specificity % (95% CI) | p | OR (95% CI) | p |
---|---|---|---|---|---|---|---|---|---|
12 mo | |||||||||
SOFA at 24 hra | 1,379 | 81.6 (75.1–88.1) | 3.3 | 4.5 | 62.3 (49.8–73.4) | 74 (71.5–76.3) | < 0.0001 | 1.203 (1.103–1.313) | < 0.001 |
SOFA at 48 hra | 968 | 85.2 (79.8–90.6) | 2.7 | 4.5 | 73.1 (59.8–83.2) | 70.9 (67.8–73.7) | < 0.0001 | 1.211 (1.105–1.327) | < 0.001 |
Mean SOFAa | 1,379 | 82.7 (76.1–89.3) | 3.4 | 4.55 | 55.7 (43.3–67.5) | 84.5 (82.4–86.3) | < 0.0001 | 1.266 (1.157–1.385) | < 0.001 |
Highest SOFAa | 1,379 | 82.7 (76.2–89.2) | 3.3 | 5.5 | 59 (46.5–70.5) | 78.9 (76.7–81.1) | < 0.0001 | 1.224 (1.131–1.325) | < 0.001 |
24 mo | |||||||||
SOFA at 24 hra | 899 | 73.3 (67.5–79.2) | 2.9 | 4.5 | 59.1 (48.7–68.8) | 71.4 (67.7–74.9) | < 0.0001 | 1.130 (1.001–1.276) | 0.048 |
SOFA at 48 hra | 652 | 75.7 (69.4–82.1) | 3.3 | 4.5 | 67.1 (55.9–76.6) | 71.9 (67.6–75.9) | < 0.0001 | 1.158 (1.024–1.310) | 0.020 |
Mean SOFAa | 899 | 73.8 (67.7–79.9) | 3.1 | 3.23 | 63.6 (53.2–72.9) | 69.8 (66.1–73.3) | < 0.0001 | 1.184 (1.038–1.350) | 0.043 |
Highest SOFAa | 899 | 74.3 (68.4–80.2) | 3 | 4.5 | 65.9 (55.5–74.9) | 66.6 (62.7–70.2) | < 0.0001 | 1.136 (1.016–1.270) | 0.025 |
OR = odds ratio, SOFA = Sequential Organ Failure Assessment.
aAdjusted for age, gender, diagnosis, procedure, comorbidities (hypertension, dyslipidemia, diabetes mellitus, ischemic cardiopathy, peripheral artery disease, cerebrovascular disease, chronic kidney disease, pulmonary disease), left ventricular function, timing of surgery, and previous cardiac surgery.
bOptimal cutoff value for the best sensitivity and specificity.