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. 2022 Mar 18;32(5):451–460. doi: 10.1038/s41422-022-00633-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a A homo-dimer of Nup205 at the center of the IR subunit is flanked by two molecules of Nup188. The two Nup205 molecules contact each other via their C-terminal helices. b A side-by-side comparison of the structures of Nup188 and Nup205. The overall appearance and size are similar between Nup188 (left panel) and Nup205 (right panel). c A close-up view on the dimeric interface between Nup205 and Nup205′. The C-terminal helices α75/α78 from Nup205 stack against the corresponding helices from Nup205′. d A close-up view on the interface between Nup205 and Nup188. Three inter-helical surface loops from Nup188 and Nup205 are involved in the interactions.