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. 2001 Jul;45(7):2147–2150. doi: 10.1128/AAC.45.7.2147-2150.2001

TABLE 1.

Genotypic and phenotypic results for macrolide-resistant S. pneumoniae

Strains No. (%) of isolates MIC (μg/ml)
Erythromycin
Clindamycin
Telithromycin
ABT-773
MIC90 Range MIC90 Range MIC90 Range MIC90 Range
erm(B)+ 100 (46.5) ≥64 1–≥64 >16 0.12–>16 0.06 ≤0.02–1 0.03 ≤0.002–0.5
mef(A)+ 105 (48.8) 4 1–≥64 0.12 0.12–0.5 0.06 ≤0.02–1 0.03 ≤0.002–0.5
erm(B)mef(A) 4 (1.9) 1–32 0.12 ≤0.002–0.004 ≤0.002
erm(B)+mef(A)+ 6 (2.8) 16–≥64 0.12–>16 ≤0.002–0.06 ≤0.002–0.03
Susceptible controlsa 24 (10) 0.25 0.06–0.25 0.12 <0.12 0.008 ≤0.002–0.008 0.004 ≤0.002–0.008
a

Included erm(B)-positive, erm(B)-negative, and mef(A)-negative strains.