Pparafl/fl and PparaΔCM mice were randomized to receive TAC or sham surgery, and analyses were performed 2 weeks later. a Fibrosis-related genes profiles. b Expression of collagen fibril organization-, ECM organization-, and cell adhesion-related genes in mouse hearts was detected by qPCR (n = 13–20). The data are expressed as the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.