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. 2022 Mar 18;32(5):437–450. doi: 10.1038/s41422-022-00632-y

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© The Author(s) 2022

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Fig. 7 — a Interaction between two Nup170 molecules from adjacent IR monomers. b Overall view of subunits from middle and inner layers involved in the inter-monomer interactions. Three interfaces are boxed by green, magenta and black dashed lines and enlarged in c, d and e, respectively. c Details of the interaction between Nup192-1/M1 and the neighboring Nup188-1/M2. d Details of the interaction between Nup192-1/M1 and the neighboring CNT-A-2/M2. e Details of the interaction between CNT-A-1/M1 and the neighboring CNT-A-2/M2. f, g Distance changes between IR monomers are shown from constricted (f) to dilated (g) states. Two views are shown and schematic diagrams are drawn at the bottom. The representative subunits of IR are color coded. The interacting subunits of each interaction in the constricted NPC (black arrows) are separated by ~7 nm in the dilated NPC (dashed lines).