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. 2022 Apr 30;8:39. doi: 10.1038/s41421-022-00399-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a–c Progressive inhibition of U87 cell proliferation by m⁶A treatment, as shown by phase light images (a), Ki67 staining (b), and CCK8 assay (c). Scale bar: 50 μm. d, e Selective preservation of a subset of GBM cells with potential stem cell-like properties. Formation of neurosphere-like structures with m⁶A treatment (d); Strong Ki67 (e, upper panel) and Sox2 staining (e, middle panel) with the neurosphere-like objects; Enhanced Tuj1 staining at the peripherals of the neurosphere-like objects (e, lower panel). Scale bar: 50 μm.