Fig. 2. (A and B) Cell migration trajectories in confined platforms with flat surfaces on both top and bottom with height of 10 (N = 67) and 15 μm (N = 68). (C and D) Trajectories of cell migration inside double-sided micropost arrays with separation height of 10 (N = 36) and 15 μm (N = 25). (E) Cell migration speed inside confined platforms with flat surfaces or micropost arrays on top and bottom. Micropost arrays on both sides of platform were 3 μm in dia. and 3 μm spacing. Statistical significance was calculated using Student's t-test (*p < 0.05 and **p < 0.01).