Table 3.
Comparison between two groups divided by serum C-peptide level at diagnosis and 15 years after diagnosis.
| Baseline | Year 15 | |||||
|---|---|---|---|---|---|---|
| C-peptide < 0.5 ng/mL(n=77) | C-peptide ≥ 0.5 ng/mL(n=157) | p value | C-peptide < 0.015 ng/mL(n=135) | C-peptide ≥ 0.015 ng/mL(n=48) | p value | |
| Laboratory findings | ||||||
| HbA1c, % | 9.67 ± 1.76 | 9.37 ± 1.90 | 0.245 | 9.69 ± 1.84 | 9.69 ± 2.15 | 0.990 |
| Total cholesterol, mg/dL | 174.8 ± 29.2 | 175.5 ± 30.5 | 0.870 | 175.4 ± 28.8 | 182.5 ± 32.7 | 0.160 |
| Triglyceride, mg/dL | 116.0 ± 82.0 | 100.9 ± 58.4 | 0.149 | 104.0 ± 62.3 | 129.7 ± 102.5 | 0.108 |
| HDL-Cholesterol, mg/dL | 56.4 ± 13.9 | 55.2 ± 12.8 | 0.530 | 56.4 ± 13.1 | 52.0 ± 15.7 | 0.064 |
| LDL-Cholesterol, mg/dL | 97.0 ± 25.3 | 101.4 ± 24.7 | 0.209 | 99.8 ± 22.3 | 107.5 ± 30.8 | 0.116 |
| Daily insulin dose, units/kg/day | 0.90 ± 0.26 | 0.76 ± 0.28 | < 0.001 | 0.88 ± 0.21 | 0.74 ± 0.37 | 0.034 |
| Diabetes complications | ||||||
| Diabetic retinopathy | 17 (22.1%) | 43 (27.4%) | 0.382 | 35 (25.9%) | 14 (31.8%) | 0.447 |
| Peripheral neuropathy | 17 (22.1%) | 37 (23.6%) | 0.799 | 34 (25.2%) | 10 (22.7%) | 0.742 |
| Diabetic nephropathy | 16 (20.8%) | 36 (22.9%) | 0.710 | 28 (20.7%) | 10 (22.7%) | 0.780 |
| Diabetic ketoacidosis | 16 (20.8%) | 23 (14.6%) | 0.237 | 32 (23.7%) | 3 (6.8%) | 0.014 |
Data are presented as mean ± SD or number of patients (%).
HbA1c, glycated hemoglobin A; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SD, standard deviation.