Fig. 19. Schematic illustration of the multiply amplified electrochemical biosensor for target DNA detection. (A) Fabrication steps of the functionalized AuNCs/GR nanohybrids; (B) principle of the target-triggered Exo III-assisted cascade target recycling; (C) construction of the biosensor using functionalized AuNC/GR nanohybrids as the interfaces of the enzyme-catalyzed silver deposition reaction. [Reprinted with permission from ref. 401, W. Wang, T. Bao, X. Zeng, H. Xiong, W. Wen, X. Zhang and S. Wang, Ultrasensitive Electrochemical DNA Biosensor Based on Functionalized Gold Clusters/Graphene Nanohybrids Coupling with Exonuclease III-Aided Cascade Target Recycling, Biosens. Bioelectron., 2017, 91, 183–189. Copyright© Elsevier.].
