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. 2019 Mar 18;9(16):8778–8881. doi: 10.1039/c8ra09577a

Graphene-based biosensors for detecting dopamine (DA), ascorbic acid (AA), and uric acid (UA)a.

Graphene-based nanocomposites Linear range (μM) Limit of detection (μM) Sensitivity Ref.
AA DA UA AA DA UA
GR 4–100 2.64 459
GR/PtNPs 0.15–34.4 0.03–8.13 0.05–11.85 0.15 0.03 0.05 0.969 460
MWCNTs/GO nanoribbons 0.1–8.5 0.15–12.15 0.15–11.4 0.06 0.08 0.07 461
MoS2-PANI/rGO nanocomposite 50–8000 5.0–500 1.0–500 22.20 0.70 0.36 458
N-doped GR 5–1300 0.5–170 0.1–20 2.2 0.25 0.045 462
Screen-printed GR 0–4500 0.5–2000 0.8–2500 0.95 0.12 0.20 463
AuNPs/β-cyclodextrin/GR 300–2000 0.50–150 0.5–50 10 0.15 0.21 464
Pd NPs/GR/CS composite 100–4000 20–200 0.5–200 20 0.1 0.17 465
N-doped carbon spheres/rGO 50–1200 0.5–90 1–70 0.65 0.012 0.018 466
GR/CS nanocomposite 0.1–140 1–125 0.05 0.1 467
Polyaniline/GO fibrous nanocomposite 25–200 2–18 2–18 20 0.5 0.2 2.0 468
Tryptophan/GR 0.2–3.4 0.5–10 10–1000 10.09 0.29 1.24 469
Polyimidazole/GO copolymer 7–2275 12–278 3.6–249.6 18 0.63 0.59 470
CTAB-GO/MWCNTs 5.0–300 5.0–500 3.0–60 1.0 1.5 1.0 471
PtNPs/GR–CNTs composite 200–900 0.1–30 0.1–50 50 0.01 0.01 9.199 472
Pristine GR 9–2314 5–710 6–1330 6.45 2.0 4.82 112.5 473
Ni–Co hexacyanoferrate/GR 0.5–2000 0.2–500 0.15 0.06 474
GR/CNTs/sulfonated CS 1.25–442 1.25–357 1.25–533 0.06 0.06 0.06 1.68 475
AgNWs/rGO 45–1550 40–450 35–300 0.81 0.26 0.30 476
rGO-CNTs/ITO 10–200 0.2–8 0.2–16 5.31 0.04 0.17 477
Au@PdNPs/rGO composite 1–800 0.1–100 0.1–350 0.28 0.024 0.02 478
N-doped GR flakes 80–2000 0.5–150 3–60 0.58 0.015 0.015 479
Hemin–GO sheets 1–100 0.5–40 0.5–50 0.3 0.17 0.17 480
Pd@Ag nanoflowers/rGO 1–4100 0.05–112 3–186 0.185 0.017 0.654 481
GR fibers/NiCo2O4 200–750 1–13 10–26 50 0.1 0.2 482
PtNPs/GR paper 0.087–100 0.005 2.00 483
GR/ZnO composite 50–2350 1–70 3–330 3.71 0.33 1.08 484
PAA/polypyrrole/GO 300–440 32–60 1.962 1.025 485
PAM/polypyrrole/GO 150–220 6–13 0.659 0.408 485
β-NiS/rGO/AuNPs 0.90–100 0.1–100 0.331 0.0045 486
AuNPs/rGO 0.05–11 0.1–11 0.02 0.03 487
CVD-grown GR 5–1500 0.25–75 0.4–120 1.58 0.06 0.09 488
3D GR hydrogel/AuNPs 1.0–700 0.2–30 1–60 0.028 0.0026 0.005 489
Ferrocene/3D GR hydrogel 20–450 10–180 8–400 0.183 0.042 0.067 490
GR/porous CS composite 1–700 1–800 0.14 0.17 491
a

Abbreviations used: HP: hydrophilic polymer, CNT: carbon nanotubes, CTAB: cetyl trimethylammonium bromide, PPy: polypyrrole, CVD: chemical vapor deposition, GRHG: graphene hydrogel, PAA: polyacrylic acid, PAM: polyacrylamide.