Fig. 2. The interaction fingerprints of the enantiomeric inhibitors with SETD7/SAM. (A) and (B) are the normalized frequency of hydrophobic interactions in the last 50 ns for (R)-PIF-2/hSETD7/SAM and (S)-PIF-2/hSETD7/SAM system, respectively. (C) and (D) are the normalized frequency of hydrogen bonds or ionic bonds in the last 50 ns for (R)-PIF-2/hSETD7/SAM and (S)-PIF-2/hSETD7/SAM system, respectively. Cyan, magenta, and bright-orange areas represent the three different MD simulations presented in this work.
