Fig. 5. Compound 11 promoted TyrRS nuclear localization in HeLa cells. Hela cells were treated with compound 11 (1.1, 3.3, 10, or 30 μM) or DMSO for 8 h. Cells cultured in serum-free media for 8 h were under serum starvation. The cytoplasmic and nuclear fractions from cells were subjected to immunoblot assays. Quantification of immunoblots is shown below.
