IC50 values of the test compounds in MCF-7 and MDA-MB-231 cells.
| Entry | Compound | MCF-7 (μM) | MDA-MB231 (μM) | Entry | Compound | MCF-7 (μM) | MDA-MB231 (μM) |
|---|---|---|---|---|---|---|---|
| 8a |
|
>100 | >100 | 8k |
|
>100 | >100 |
| 8b |
|
37.42 | >100 | 8l |
|
>100 | >100 |
| 8c |
|
>100 | >100 | 8m |
|
>100 | >100 |
| 8d |
|
45.3 | >100 | 8n |
|
>100 | >100 |
| 8e |
|
50 | >100 | 8o |
|
>100 | >100 |
| 8f |
|
>100 | >100 | 8p |
|
>100 | >100 |
| 8g |
|
>100 | >100 | 8q |
|
>100 | >100 |
| 8h |
|
>100 | >100 | 8r |
|
42.11 | >100 |
| 8i |
|
>100 | >100 | Plumbagin | 3.5 | 4.4 | |
| 8j |
|
>100 | >100 | Peganumine A7 | 38.5 | — | |
| Tamoxifen | 50 | 75 |