Table 1.

Stabilizing effects of shuttling factors on ERAD substrates measured by Leto et al. (36)

Gene	A1ATNHK-GFP		GFP-RTAE177Q		INSIG1-GFP		GFPu
	Effect size	p	Effect size	p	Effect size	p	Effect size	p
Ddi1	−6.0 to −0.2	0.569	−1.8 to 0.8	0.661	−2.5 to 1.4	0.903	−0.6 to 2	0.742
Ddi2	0.9–1.9	0.0213	1.6–3.0	0.000002	2.3–3.6	0.000002	2.3–3.4	0.000002
Rad23A	−0.7 to 1.8	0.863	0.5–1.4	0.0239	0.2–3.7	0.444	−3.6 to 1.4	0.941
Rad23B	1.2–5.4	0.0316	0.5–1.6	0.0273	−3.0 to 4.0	0.720	−2.7 to 1.9	0.754
UBQLN1	−1.6 to 1.1	0.831	−3.5 to 1.4	0.931	−1.1 to 1.8	0.922	−3.1 to 1.4	0.730
UBQLN2	−1.8 to 1.2	0.984	−2.0 to 0.7	0.889	−1.6 to 1.3	0.917	−2.6 to 1.3	0.824
UBQLN3	−2.5 to 1.7	0.846	−2.0 to 0.5	0.699	0.1 to 2.5	0.417	−2.5 to 2.0	0.761
UBQLN4	0.5–1.8	0.171	−2.8 to 1.2	0.724	0.7–2.0	0.0315	0.4–3.4	0.183
UBL7	0.3–5.0	0.531	−2.8 to 1.1	0.931	0.4–1.5	0.174	−4.5 to 1.5	0.602

Bold highlights effects that surpassed the false discovery rate correction for significance.