Table 1.
Baseline characteristics of patients with TAVI-related infective endocarditis
| Baseline characteristics |
Total
( n = 733) |
TAVI-IE
( n = 17) |
TAVI-NIE
( n = 716) |
p value |
|---|---|---|---|---|
| Demographics | ||||
| Age | 80.7 ± 10.2 | 78.7 ± 13.7 | 80.8 ± 10.1 | 0.54 |
| Male | 422 (57.5) | 12 (70.5) | 410 (57.2) | 0.32 |
| Procedural risk | ||||
| STS-PROM | 5.9 ± 4.6 | 5.7 ± 4.8 | 6.0 ± 4.6 | 0.84 |
| EuroSCORE II | 5.1 ± 5.8 | 4.8 ± 5.3 | 5.1 ± 5.8 | 0.83 |
| Past medical history | ||||
| Hypertension | 512 (69.8) | 12 (70.5) | 500 (69.8) | 0.94 |
| Dyslipidaemia | 514 (70.1) | 12 (70.5) | 502 (70.1) | 0.96 |
| Diabetes mellitus | 165 (22.5) | 4 (23.5) | 161 (22.4) | 0.91 |
| COPD | 148 (20.1) | 2 (11.7) | 146 (20.3) | 0.38 |
| Prior stroke | 42 (5.7) | 1 (5.8) | 41 (5.7) | 0.97 |
| Atrial fibrillation/ flutter | 271 (36.9) | 7 (41.1) | 264 (36.8) | 0.71 |
| Coronary artery disease | ||||
| CABG | 144 (19.6) | 6 (35.2) | 138 (19.2) | 0.1 |
| PCI | 229 (31.2) | 6 (35.2) | 223 (31.1) | 0.71 |
| Previous valve procedure | ||||
| Prior SAVR | 27 (3.6) | 1 (5.8) | 26 (3.6) | 0.47 |
| MV repair/ replacement | 20 (2.7) | 0 (0) | 20 (2.7) | 1.0 |
| Prior IE | 4 (0.5) | 0 (0) | 4 (0.5) | 1.0 |
| Permanent pacemaker | 68 (9.2) | 2 (11.7) | 66 (9.2) | 0.66 |
| ICD | 13 (1.7) | 0 (0) | 13 (1.8) | 1.0 |
| Baseline creatinine clearance | 55.9 ± 23.8 | 68.9 ± 37.5 | 55.5 ± 23.3 | 0.02 |
| LVEF | 50.5 ± 11.2 | 50.5 ± 11.3 | 50.5 ± 11.2 | 0.98 |
Value are presented as mean ± standard deviation or n (%)
IE infective endocarditis, NIE no infective endocarditis, STS-PROM Society of Thoracic Surgeons Predicted Risk of Mortality, EuroSCORE European System for Cardiac Operative Risk Evaluation, CABG coronary artery bypass graft, PCI percutaneous coronary intervention, SAVR surgical aortic valve replacement, MV mitral valve, ICD implantable cardiac defibrillator, COPD chronic obstructive pulmonary disease; creatinine clearance [mL/min], LVEF left ventricular ejection fraction