Time-kill analysis of ABT-773 at antibiotic concentrations equal to four times the MIC against S. pneumoniae ATCC 6303 (A), H. influenzae 1882 (B), M. catarrhalis 2604 (C), and S. aureus ATCC 6538P (D); MICs are presented in Table 4. ■, drug-free control in medium; □, ABT-773 at four times the MIC in medium; ●, drug-free control in medium containing 50% human serum, ○, ABT-773 at four times the MIC in medium containing 50% human serum.