TABLE 3.
Adjusted associations of cannabis and tobacco with pre-bronchodilator impulse oscillometry (IOS) measures for the whole sample
| R 5 | R 20 | R5−R20 | X 5 | AX | f res | |
| Participants (n) | 877 | 877 | 877 | 876 | 868 | 870 |
| Joint-years | ||||||
| β (95% CI) | 0.104 (0.033–0.175) | 0.073 (−0.001–0.148) | 0.086 (0.013–0.158) | 0.110 (0.039–0.174) | 0.130 (0.060–0.200) | 0.133 (0.062–0.204) |
| p-value | 0.004 | 0.054 | 0.020 | 0.002 | <0.001 | <0.001 |
| Pack-years | ||||||
| β (95% CI) | 0.042 (−0.029–0.113) | 0.003 (−0.072–0.077) | 0.076 (0.004–0.149) | 0.041 (−0.027–0.108) | 0.052 (−0.018–0.123) | 0.047 (−0.025–0.119) |
| p-value | 0.248 | 0.946 | 0.039 | 0.237 | 0.147 | 0.197 |
| Interaction term# (p-value) | 0.031 | 0.131 | 0.034 | 0.062 | 0.034 | 0.054 |
All IOS measures are log-transformed and analyses are adjusted for use of both substances and also adjusted for sex, body mass index and height. Bolded values are statistically significant. β-values are standardised regression coefficients, which represent the standard deviation difference in IOS measure associated with each standard deviation change in joint- or pack-years. R5: resistance at 5 Hz; R20: resistance at 20 Hz; R5−R20: difference between R5 and R20; X5: reactance at 5 Hz; AX: area under the reactance curve between 5 Hz and resonant frequency (fres). #: interaction term p-values are for joint-years by sex in the adjusted model for each IOS measure tested for after the adjusted model was run.