TABLE 5.
Longitudinal analyses of cannabis and tobacco use between ages 38 and 45 years with pre-bronchodilator impulse oscillometry (IOS) measures for the whole sample
| R 5 | R 20 | R5−R20 | X 5 | AX | f res | |
| Participants (n) | 864 | 864 | 864 | 862 | 856 | 857 |
| Joint-years 38–45 years | ||||||
| β (95% CI) | 0.078 (0.023–0.132) | 0.060 (−0.002–0.121) | 0.043 (−0.014–0.100) | 0.059 (0.003–0.114) | 0.076 (0.023–0.129) | 0.091 (0.037–0.145) |
| p-value | 0.005 | 0.056 | 0.140 | 0.038 | 0.005 | 0.001 |
| Pack-years 38–45 years | ||||||
| β (95% CI) | 0.017 (−0.038–0.072) | −0.004 (−0.066–0.058) | 0.044 (−0.014–0.101) | 0.048 (−0.009–0.104) | 0.037 (−0.016–0.091) | 0.015 (−0.040–0.069) |
| p-value | 0.553 | 0.903 | 0.134 | 0.099 | 0.173 | 0.601 |
All IOS measures are log-transformed. Analyses are adjusted for use of both substances and also adjusted for sex, body mass index, height and the relevant IOS measure at age 38 years (e.g. resistance at 5 Hz (R5) at 38 years is the adjustment for age 45 years R5); bolded values are statistically significant. β-values are standardised regression coefficients, which represent the standard deviation difference in IOS measure associated with each standard deviation change in joint- or pack-years. R20: resistance at 20 Hz; R5−R20: difference between R5 and R20; X5: reactance at 5 Hz; AX: area under the reactance curve between 5 Hz and resonant frequency (fres).