Fig. 3. miR-148b overexpression suppressed cell proliferation and induced apoptosis in AML cells. (A–C) miR-148b expression was detected by qRT-PCR in HL60, THP-1, and NB4 cells transfected with miR-148b or miR-con for 48 h. (D–F) Cell proliferation was assessed by CCK-8 assay in HL60, THP-1, and NB4 cells transfected with miR-148b or miR-con for 24, 48, and 72 h. (G) Apoptosis of miR-148b- or miR-con-transfected HL60 and THP-1 cells was analyzed by flow cytometry analysis. *P < 0.05 vs. si-con.
